Clinico-pathological characteristics of central nervous system tumors in a South American center from 2010 to 2015

Authors

  • Esteban Jaramillo-Jiménez Instituto Neurológico de Colombia (INDEC), Universidad CES https://orcid.org/0000-0002-9720-096X
  • Cristian Vargas-García The University of Western Australia https://orcid.org/0000-0002-8859-0070
  • Iader Rodríguez-Márquez Instituto Neurológico de Colombia (INDEC), Universidad CES https://orcid.org/0000-0002-2270-7088
  • Juliana Sandoval-Barrios Universidad Pontificia Bolivariana
  • David Gómez-Duque Instituto Neurológico de Colombia (INDEC)
  • Hernán Barrientos-Montoya Instituto Neurológico de Colombia (INDEC)
  • Julián Arango-Vélez Instituto Neurológico de Colombia (INDEC)
  • Tatiana Gómez-Escobar Instituto Neurológico de Colombia (INDEC), Universidad CES
  • Mónica Massaro-Ceballos Universidad CES http://orcid.org/0000-0003-4750-6968
  • Marta Jiménez-Jaramillo Instituto Neurológico de Colombia (INDEC), Universidad CES

DOI:

https://doi.org/10.21615/cesmedicina.34.2.2

Keywords:

Nervous system neoplasms, Brain neoplasms, Epidemiology, Pathology

Abstract

Objective: The aim of this study was to characterize patients with a diagnosis of a central nervous system (CNS) tumors at the Instituto Neurologico de
Colombia during the period between 2010 to 2015. Methods: A retrospective descriptive study was conducted. The Classification of the World Health Organization was used for CNS primary tumors whereas the  International Classification of Diseases for oncology (ICD-O) was used for CNS metastatic tumors. Results: 288 patients were identified, 194 of them with primary tumors of CNS and 94 with metastatic tumors from systemic cancer. It was not possible to classify primary tumors in 23.7 % of the cases and regarding the metastatic tumors it was not possible to obtain the classification in 35.1 % of the cases. Men presented more frequently  tumors of malignant behavior such as glioblastoma NOS (not otherwise specified) (14.9 %) while in women benign behavior tumors such as meningioma predominated (23.2 %). For population older than 65 years old, both glioblastoma NOS and meningioma were more frequent in women with 17.4 % and 28.3 %, respectively. In patients with CNS metastatic tumors, according to the topographic classification, the most frequent primary tumors were lung (39.4 %), followed by breast (17 %). Its origin was not identified in 11.7 % of the cases. The most identified histology was adenocarcinoma (14.9 %), followed by carcinoma (8.5 %). Conclusion: For disease surveillance, it is necessary to complete  epidemiological and clinical monitoring of primary and metastatic tumors of the CNS by using institutional cancer registries including topographic, histological and molecular data according to availability.

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Published

2020-10-22

How to Cite

Jaramillo-Jiménez, E., Vargas-García, C., Rodríguez-Márquez, I., Sandoval-Barrios, J., Gómez-Duque, D., Barrientos-Montoya, H., … Jiménez-Jaramillo, M. (2020). Clinico-pathological characteristics of central nervous system tumors in a South American center from 2010 to 2015. CES Medicina, 34(2), 103–113. https://doi.org/10.21615/cesmedicina.34.2.2

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Artículo original de investigación científica o tecnológica
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