Langerhans cell Histiocytosis and diagnostic images
Abstract
The goal of this article is to provide readers with a case presentation of a patient who presented to the radiology department for pain located at the costal region, which later was diagnosed as Langerhans cell histiocytosis (LCH). We pretend with this article to provide a brief, complete and efficient literature review regarding the topic of imaging on this pathology. This was done with the objective of providing the reader with a brief and concise literature review so that this disease entity can remain within the list of differencials.Downloads
Download data is not yet available.
References
Mohammed A, Abdullahi K, Mohammed U, Aliyu HO, Liman AA, Abdullahi S, et al. Disseminated Langerhan's cell histiocytosis: a case report and review of the literature. Annals of African medicine. 2011 ;10(4):310-3.. https://www.ncbi.nlm.nih.gov/pubmed/22064259
Klemke CD, Dippel E, Geilen CC, Koenigsmann MP, Thiel E, Orfanos CE, et al. Atypical generalized eruptive histiocytosis associated with acute monocytic leukemia. Journal of the American Academy of Dermatology. 2003 Nov;49(5 Suppl):S233-6.. http://www.jaad.org/article/S0190-9622(03)00037-9/abstract
Zhong WQ, Jiang L, Ma QJ, Liu ZJ, Liu XG, Wei F, et al. Langerhans cell histiocytosis of the atlas in an adult. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2010 Jan;19(1):19-22.. https://www.ncbi.nlm.nih.gov/pubmed/19844749
Wilejto M, Abla O. Langerhans cell histiocytosis and Erdheim-Chester disease. Current opinion in rheumatology. 2012 Jan;24(1):90-6. https://www.ncbi.nlm.nih.gov/pubmed/22157416
Sieben NL, Macropoulos P, Roemen GM, Kolkman-Uljee SM, Jan Fleuren G, Houmadi R, et al. In ovarian neoplasms, BRAF, but not KRAS, mutations are restricted to low-grade serous tumours. The Journal of pathology. 2004 Mar;202(3):336-40. https://www.ncbi.nlm.nih.gov/pubmed/14991899
Singer G, Oldt R, 3rd, Cohen Y, Wang BG, Sidransky D, Kurman RJ, et al. Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma. Journal of the National Cancer Institute. 2003 Mar 19;95(6):484-6. https://www.ncbi.nlm.nih.gov/pubmed/12644542
Lupi C, Giannini R, Ugolini C, Proietti A, Berti P, Minuto M, et al. Association of BRAF V600E mutation with poor clinicopathological outcomes in 500 consecutive cases of papillary thyroid carcinoma. The Journal of clinical endocrinology and metabolism. 2007 Nov;92(11):4085-90.. https://www.ncbi.nlm.nih.gov/pubmed/17785355
Mayr D, Hirschmann A, Lohrs U, Diebold J. KRAS and BRAF mutations in ovarian tumors: a comprehensive study of invasive carcinomas, borderline tumors and extraovarian implants. Gynecologic oncology. 2006 Dec;103(3):883-7. https://www.ncbi.nlm.nih.gov/pubmed/16806438
Campo E, Swerdlow SH, Harris NL, Pileri S, Stein H, Jaffe ES. The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications. Blood. 2011; 117(19):5019-32.. http://www.bloodjournal.org/content/117/19/5019?sso-checked=true
Yildirim-Baylan M, Cureoglu S, Paparella MM. Temporal Bone Histopathology Case of the Month: Langerhans’ Cell Histiocytosis of the Temporal Bone. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2012;33(2):10.1097/MAO.0b013e31821a80f8.
Juvet SC, Hwang D, Downey GP. Rare lung diseases III: Pulmonary Langerhans’ cell histiocytosis. Canadian Respiratory Journal : Journal of the Canadian Thoracic Society. 2010 May-Jun;17(3):e55-e62. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900147/
Xia CX, Li R, Wang ZH, Lv FJ, Tang XQ, Li QF, et al. A rare cause of goiter: Langerhans cell histiocytosis of the thyroid. Endocrine journal. 2012;59(1):47-54. https://www.ncbi.nlm.nih.gov/pubmed/22019948
Azouz EM, Saigal G, Rodriguez M, Podda A. Langerhans’ cell histiocytosis: pathology, imaging and treatment of skeletal involvement. Pediatr Radiol. 2005 2005/02/01;35(2):103-15. https://www.ncbi.nlm.nih.gov/pubmed/15289942
Stull MA, Kransdorf MJ, Devaney KO. Langerhans cell histiocytosis of bone. RadioGraphics. 1992 1992/07/01;12(4):801-23. https://www.ncbi.nlm.nih.gov/pubmed/1636041
Grois N, Potschger U, Prosch H, Minkov M, Arico M, Braier J, et al. Risk factors for diabetes insipidus in langerhans cell histiocytosis. Pediatric blood & cancer. 2006 Feb;46(2):228-33. https://www.ncbi.nlm.nih.gov/pubmed/16047354
Hung PC, Wang HS, Jaing TH, Huang TJ, Pang LC. From normal to abnormal MR findings within three weeks in a solitary pelvic Langerhans histiocytosis. Skeletal radiology. 2003 Aug;32(8):481-4. http://link.springer.com/article/10.1007/s00256-003-0637-x
Huang WD, Yang XH, Wu ZP, Huang Q, Xiao JR, Yang MS, et al. Langerhans cell histiocytosis of spine: a comparative study of clinical, imaging features, and diagnosis in children, adolescents, and adults. The spine journal : official journal of the North American Spine Society. 2013 Sep;13(9):1108-17. https://www.ncbi.nlm.nih.gov/pubmed/23602327
Hwang S, Panicek DM. The evolution of musculoskeletal tumor imaging. Radiologic clinics of North America. 2009 May;47(3):435-53. https://www.ncbi.nlm.nih.gov/pubmed/19361669
National Cancer Institute: PDQ® Langerhans Cell Histiocytosis Treatment. Bethesda, MD: National Cancer Institute. Date last modified <01/30/2015>. Available at: http://cancer.gov/cancertopics/pdq/treatment/lchistio/HealthProfessional.
Klemke CD, Dippel E, Geilen CC, Koenigsmann MP, Thiel E, Orfanos CE, et al. Atypical generalized eruptive histiocytosis associated with acute monocytic leukemia. Journal of the American Academy of Dermatology. 2003 Nov;49(5 Suppl):S233-6.. http://www.jaad.org/article/S0190-9622(03)00037-9/abstract
Zhong WQ, Jiang L, Ma QJ, Liu ZJ, Liu XG, Wei F, et al. Langerhans cell histiocytosis of the atlas in an adult. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2010 Jan;19(1):19-22.. https://www.ncbi.nlm.nih.gov/pubmed/19844749
Wilejto M, Abla O. Langerhans cell histiocytosis and Erdheim-Chester disease. Current opinion in rheumatology. 2012 Jan;24(1):90-6. https://www.ncbi.nlm.nih.gov/pubmed/22157416
Sieben NL, Macropoulos P, Roemen GM, Kolkman-Uljee SM, Jan Fleuren G, Houmadi R, et al. In ovarian neoplasms, BRAF, but not KRAS, mutations are restricted to low-grade serous tumours. The Journal of pathology. 2004 Mar;202(3):336-40. https://www.ncbi.nlm.nih.gov/pubmed/14991899
Singer G, Oldt R, 3rd, Cohen Y, Wang BG, Sidransky D, Kurman RJ, et al. Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma. Journal of the National Cancer Institute. 2003 Mar 19;95(6):484-6. https://www.ncbi.nlm.nih.gov/pubmed/12644542
Lupi C, Giannini R, Ugolini C, Proietti A, Berti P, Minuto M, et al. Association of BRAF V600E mutation with poor clinicopathological outcomes in 500 consecutive cases of papillary thyroid carcinoma. The Journal of clinical endocrinology and metabolism. 2007 Nov;92(11):4085-90.. https://www.ncbi.nlm.nih.gov/pubmed/17785355
Mayr D, Hirschmann A, Lohrs U, Diebold J. KRAS and BRAF mutations in ovarian tumors: a comprehensive study of invasive carcinomas, borderline tumors and extraovarian implants. Gynecologic oncology. 2006 Dec;103(3):883-7. https://www.ncbi.nlm.nih.gov/pubmed/16806438
Campo E, Swerdlow SH, Harris NL, Pileri S, Stein H, Jaffe ES. The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications. Blood. 2011; 117(19):5019-32.. http://www.bloodjournal.org/content/117/19/5019?sso-checked=true
Yildirim-Baylan M, Cureoglu S, Paparella MM. Temporal Bone Histopathology Case of the Month: Langerhans’ Cell Histiocytosis of the Temporal Bone. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2012;33(2):10.1097/MAO.0b013e31821a80f8.
Juvet SC, Hwang D, Downey GP. Rare lung diseases III: Pulmonary Langerhans’ cell histiocytosis. Canadian Respiratory Journal : Journal of the Canadian Thoracic Society. 2010 May-Jun;17(3):e55-e62. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900147/
Xia CX, Li R, Wang ZH, Lv FJ, Tang XQ, Li QF, et al. A rare cause of goiter: Langerhans cell histiocytosis of the thyroid. Endocrine journal. 2012;59(1):47-54. https://www.ncbi.nlm.nih.gov/pubmed/22019948
Azouz EM, Saigal G, Rodriguez M, Podda A. Langerhans’ cell histiocytosis: pathology, imaging and treatment of skeletal involvement. Pediatr Radiol. 2005 2005/02/01;35(2):103-15. https://www.ncbi.nlm.nih.gov/pubmed/15289942
Stull MA, Kransdorf MJ, Devaney KO. Langerhans cell histiocytosis of bone. RadioGraphics. 1992 1992/07/01;12(4):801-23. https://www.ncbi.nlm.nih.gov/pubmed/1636041
Grois N, Potschger U, Prosch H, Minkov M, Arico M, Braier J, et al. Risk factors for diabetes insipidus in langerhans cell histiocytosis. Pediatric blood & cancer. 2006 Feb;46(2):228-33. https://www.ncbi.nlm.nih.gov/pubmed/16047354
Hung PC, Wang HS, Jaing TH, Huang TJ, Pang LC. From normal to abnormal MR findings within three weeks in a solitary pelvic Langerhans histiocytosis. Skeletal radiology. 2003 Aug;32(8):481-4. http://link.springer.com/article/10.1007/s00256-003-0637-x
Huang WD, Yang XH, Wu ZP, Huang Q, Xiao JR, Yang MS, et al. Langerhans cell histiocytosis of spine: a comparative study of clinical, imaging features, and diagnosis in children, adolescents, and adults. The spine journal : official journal of the North American Spine Society. 2013 Sep;13(9):1108-17. https://www.ncbi.nlm.nih.gov/pubmed/23602327
Hwang S, Panicek DM. The evolution of musculoskeletal tumor imaging. Radiologic clinics of North America. 2009 May;47(3):435-53. https://www.ncbi.nlm.nih.gov/pubmed/19361669
National Cancer Institute: PDQ® Langerhans Cell Histiocytosis Treatment. Bethesda, MD: National Cancer Institute. Date last modified <01/30/2015>. Available at: http://cancer.gov/cancertopics/pdq/treatment/lchistio/HealthProfessional.
Downloads
Published
2016-11-30
How to Cite
Rosas Saldarriaga, S. (2016). Langerhans cell Histiocytosis and diagnostic images. CES Medicina, 30(2), 231–237. Retrieved from https://revistas.ces.edu.co/index.php/medicina/article/view/3252
Issue
Section
Reporte de caso
License
Derechos de reproducción (copyright)
Cada manuscrito se acompañará de una declaración en la que se especifique que los materiales son inéditos, que no han sido publicados anteriormente en formato impreso o electrónico y que no se presentarán a ningún otro medio antes de conocer la decisión de la revista. En todo caso, cualquier publicación anterior, sea en forma impresa o electrónica, deberá darse a conocer a la redacción por escrito.
Plagios, duplicaciones totales o parciales, traduccones del original a otro idioma son de responsabilidad exclusiva de los autores el envío.
Los autores adjuntarán una declaración firmada indicando que, si el manuscrito se acepta para su publicación, los derechos de reproducción son propiedad exclusiva de la Revista CES Medicina.
Se solicita a los autores que proporcionen la información completa acerca de cualquier beca o subvención recibida de una entidad comercial u otro grupo con intereses privados, u otro organismo, para costear parcial o totalmente el trabajo en que se basa el artículo.
Los autores tienen la responsabilidad de obtener los permisos necesarios para reproducir cualquier material protegido por derechos de reproducción. El manuscrito se acompañará de la carta original que otorgue ese permiso y en ella debe especificarse con exactitud el número del cuadro o figura o el texto exacto que se citará y cómo se usará, así como la referencia bibliográfica completa.
| Article metrics | |
|---|---|
| Abstract views | |
| Galley vies | |
| PDF Views | |
| HTML views | |
| Other views | |
