Efficacy of the association oxitetracicline – isometamidium on the control of bovine anaplasmosis and tripanosomosis

Authors

  • Jesús Antonio Betancourt Echeverri Universidad Industrial de Santander
  • Gustavo López Valencia Investigador Independiente
  • Gustavo Alonso López Sierra Grupo GSBPO
  • Elias Ascanio Evanoff Universidad Central de Venezuela
  • William Berrío Cataño Politécnico Colombiano Jaime Isaza Cadavid
  • Jorge Gómez Oquendo Politécnico Colombiano Jaime Isaza Cadavid
  • Andrés Felipe Velásquez Arboleda Politécnico Colombiano Jaime Isaza Cadavid

DOI:

https://doi.org/10.21615/cesmvz.15.2.4

Keywords:

bovine, field, haemoparasites, chemotherapy

Abstract

Objective. To evaluate the efficacy of the association Isometamidium Chloride + Oxytetracycline Hydrochloride (Isopan® Reveex Laboratories, Venezuela) on the control of infections by Trypanosoma vivax and Anaplasma marginale in bovine.Materials and methods. Twelve one-year old heifers were rando-mly assigned to two groups of six animals each. Heifers on one group were each inoculated intravenously with 10 mL of blood showing a 3.5% para-sitemia with Anaplasma marginale on stained blood smears. Heifers in the other group were inoculated intravenously with five mL of blood containing a field strain of T. vivax with a parasitemia of 3 flagellates per microscopic field in a stained blood smear. In all heifers, rectal temperature, haemato-crit and parasitemia were monitored daily or every other day until days 49 post inoculation and 27 post treatment in the case of A. marginale and 11 post inoculation and 21 post treatment in the case of T. vivax. Results. The association oxitetracicline-isometamidium was 100% efficacious against T. vivax from day one after administration and until the 21th experimental day. The association showed an average efficacy of 75.59% against A. mar-ginale, though four heifers required a second treatment against Anaplasma between days 10 and 27 after treatment. Conclusions. The association Oxi-tetracicline – isometamidium showed a 100% efficacy against T. vivax and an average of 75.59% efficacy against A. marginale but did not prevent a second anaplasmosis episode between days 10 and 27 following the first treatment.

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Published

2020-08-31

How to Cite

Betancourt Echeverri, J. A., López Valencia, G., López Sierra, G. A., Evanoff, E. A., Berrío Cataño, W., Gómez Oquendo, J., & Velásquez Arboleda, A. F. (2020). Efficacy of the association oxitetracicline – isometamidium on the control of bovine anaplasmosis and tripanosomosis. CES Medicina Veterinaria Y Zootecnia, 15(2), 49–63. https://doi.org/10.21615/cesmvz.15.2.4

Issue

Vol. 15 No. 2 (2020): CES Medicina Veterinaria y Zootecnia

Section

ARTÍCULO ORIGINAL DE INVESTIGACIÓN

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Copyright (c) 2020 CES Medicina Veterinaria y Zootecnia

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