Guided tissue regeneration with fibrin rich platelet in aggressive periodontitis patient: case report

Authors

DOI:

https://doi.org/10.21615/cesodon.34.1.12

Keywords:

Platelet Rich Fibrin, Aggressive Periodontitis, Bone Regeneration, case report (Desh Bireme)

Abstract

Platelet concentrates are autologous bioactive substances that have which has an important role clinical in the periodontal tissue regeneration. This
article shows the case of a patient the patient had been diagnosed with aggressive periodontitis. The patient was treated by pharmacotherapy (docycline) and he underwent double surgeries. In the first surgical intervention was scaling and root planing with additional soft- tissue curettage. And the second surgical, tissue guided regeneration was performed using allograft and platelet rich plasma. Treatment generated satisfactory clinical outcomes in terms of probing depth reduction, clinical attachment level gain and radiographic bone fill. The data were recorded at base line, reevaluation, and 4 months post-surgery. 

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Author Biographies

Diana Lucia Bettin-Yanez, Universidad del Sinú

Odontóloga Universidad del Sinú-Montería, Periodoncista Fundación Universitaria San Martin. Docente Universidad del Sinú- Montería, Programa de Odontología, Facultad de Ciencias de la salud.

Zulieth Del Carmen Lopez, Universidad del Sinú

Odontóloga Universidad de Cartagena, Magister en Biología bucal con énfasis en histología y embriología, Universidad Estadual de Campinas. Docente Universidad del Sinú-Cartagena, Facultad de Ciencias de la Salud, Departamento de Ciencias Básicas.

References

Ramich T, Asendorf A, Nickles K, et al. Inflammatory serum markers up to 5 years after comprehensive periodontal therapy. Clin Oral Investig. 2018;27(10):18–2398.

Taiete T, Monteiro MF, Casati MZ, do Vale HF, Ambosano GMB, Nociti FH, et al. Local IL-10 level as a predictive factor in generalized aggressive periodontitis treatment response. Scand J Immunol. 2019;90(6):e12816.

Bäumer A, Kappesz D, Ozga AK, Mertens C, Eickholz P, Pretzl B. Oral health-related quality of life and standard of treatment in aggressive periodontitis patients more than 5 years after therapy. J Clin Periodontol. 2018;45(11):1347–1355.

Albandar JM. Aggressive periodontitis: Case definition and diagnostic criteria. Periodontol 2000. 2014;65(1):13-26.

Gupta G. Clinical and radiographic evaluation of intra-bony defects in localized aggressive periodontitis patients with platelet rich plasma/hydroxyapatite graft: A comparative controlled clinical trial. Contemp Clin Dent. 2014;5(4):445-451.

Corbella S, Weinstein R, Francetti L, Taschieri S, Del Fabbro M. Periodontal regeneration in aggressive periodontitis patients: A systematic review of the literature. J Investig Clin Dent. 2017;8(4):1–8.

Stähli A, Strauss FJ, Gruber R. The use of platelet-rich plasma to enhance the outcomes of implant therapy: A systematic review. Clin Oral Implants Res. 2018;29 Suppl 18(Suppl Suppl 18):20-36.

Caruana A, Savina D, Macedo JP, Soares SC. From Platelet-Rich Plasma to Advanced Platelet-Rich Fibrin: Biological Achievements and Clinical Advances in Modern Surgery. Eur J Dent. 2019;13(2):280–286.

Saleem M, Pisani F, Zahid FM, Georgakopoulos I, Pustina-Krasniqi T, Xhajanka E, et al. Adjunctive platelet-rich plasma (PRP) in infrabony regenerative treatment: A systematic review and RCT’s meta-analysis. Stem Cells Int. 2018;2018:9594235.

Strauss FJ, Nasirzade J, Kargarpoor Z, Stähli A, Gruber R. Effect of platelet-rich fibrin on cell proliferation, migration, differentiation, inflammation, and osteoclastogenesis: a systematic review of in vitro studies. Clin Oral Investig. 2020;24(2):569-584.

Preeja C, Arun S. Platelet-rich fibrin: Its role in periodontal regeneration. Saudi Journal for Dental Research. 2014; 5( 2):117-122.

Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJJ, Mouhyi J, et al. Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part III: Leucocyte activation: A new feature for platelet concentrates? Oral Surgery, Oral Med Oral Pathol Oral Radiol Endodontology. 2006;101(3):e51-e55.

Medikeri R, Meharwade V, Sinha K. Effects of recombinant human bone morphogenetic protein-2 compared to other biomaterials in the treatment of intrabony defects in periodontitis patients: A systematic review. Journal of Indian Society of Periodontology. 2019;23(4):311-315.

Utomo DN, Hernugrahanto KD, Edward M, Widhiyanto L, Mahyudin F. Combination of bone marrow aspirate, cancellous bone allograft, and platelet-rich plasma as an alternative solution to critical-sized diaphyseal bone defect: A case series. Int J Surg Case Rep. 2019; 58:178-185.

Pappalardo S, Guarnieri R. Efficacy of Platelet-Rich-Plasma (PRP) and Highly Purified Bovine Xenograft (Laddec®) Combination in Bone Regeneration after Cyst Enucleation: Radiological and Histological Evaluation. J Oral Maxillofac Res. 2013; 4(3).

Armitage GC. Development of a classification system for periodontal diseases and conditions. Annals of periodontology / the American Academy of Periodontology. 1999;4(1):1-6.

G. Caton J, Armitage G, Berglundh T, Chapple ILC, Jepsen S, S. Kornman K, et al. A new classification scheme for periodontal and peri-implant diseases and conditions – Introduction and key changes from the 1999 classification. J Clin Periodontol. 2018;45 Suppl 20:S1-S8.

Rabelo CC, Feres M, Gonçalves C, Figueiredo LC, Faveri M, Tu YK, et al. Systemic antibiotics in the treatment of aggressive periodontitis. A systematic review and a Bayesian Network meta-analysis. J Clin Periodontol. 2015;42(7):647–657.

Spasovski S, Belazelkoska Z, Popovska M, Atanasovska-Stojanovska A, Radojkova-Nikolovska V, Muratovska I, et al. Clinical therapeutic effects of the application of doxycycline in the treatment of periodontal disease. Open Access Maced J Med Sci. 2016;4(1):152–157.

Miller KAFS, Branco-de-Almeida LS, Wolf S, Hovencamp N, Treloar T, Harrison P, et al. Long-term clinical response to treatment and maintenance of localized aggressive periodontitis: a cohort study. J Clin Periodontol. 2017;44(2):158-168.

Hamasni FM, Hajj F El, Abdallah R. Single sitting surgical treatment of generalized aggressive periodontitis using gtr technique and immediate implant placement with 10-year follow-up. Case Rep Dent. 2018;2018:1–5.

Aggour RL, Abd El-Hady HMG. Platelet-Rich Fibrin for the Treatment of Intrabony Periodontal Defects in Patients with Generalized Aggressive Periodontitis: A Randomized Controlled Clinical Study. J Int Acad Periodontol [Internet]. 2017;19(1):28–34.

Thorat M, Baghele O, PS R. Adjunctive Effect of Autologous Platelet-Rich Fibrin in the Treatment of Intrabony Defects in Localized Aggressive Periodontitis Patients: A Randomized Controlled Split-Mouth Clinical Trial. Int J Periodontics Restorative Dent. 2017;37(6):e302–309.

Almutairi AS. A descriptive analysis of patient’s preferences in bone graft therapy in dentistry. Int J Health Sci (Qassim) [Internet]. 2019;13(3):24–28.

Muñoz F, Jiménez C, Espinoza D, Vervelle A, Beugnet J, Haidar Z. Use of leukocyte and platelet-rich fibrin (L-PRF) in periodontally accelerated osteogenic orthodontics (PAOO): Clinical effects on edema and pain. J Clin Exp Dent. 2016;8(2):e119–124.

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Published

2021-06-15

How to Cite

1.
Bettin-Yanez DL, Lopez ZDC. Guided tissue regeneration with fibrin rich platelet in aggressive periodontitis patient: case report. CES odontol. [Internet]. 2021 Jun. 15 [cited 2024 May 17];34(1):125-3. Available from: https://revistas.ces.edu.co/index.php/odontologia/article/view/5474

Issue

Vol. 34 No. 1 (2021): CES Odontología

Section

Reporte de casos

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Copyright (c) 2021 CES Odontología

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