Clinical, histological and histochemical description of equine pemphigus foliaceus: a case report

Abstract

The aim of this study was to describe the clinical, gross and microscopiclesions as diagnostic methods pemphigus foliaceus (PF) in an importedhorse Silla Argentino, castrated male, 9 years old from the municipalityof Montería (Córdoba, Colombia). In describing the clinical case, the presenceof scabs generalized mainly at the level of the chest and abdomen,initially presented ventral edema and some areas had pustules and vesicles,as well as fever and marked pruritus was observed. The lesions werelocated bilaterally at the level of face, thoracic region, abdominal, glutealand limbs. Histopathological in the HE stain, was observed the presence ofacantholytic keratinocytes and areas acantholytic sloughing in the granularlayer, hyperplasia and epidermal desquamation; areas subepidermalspongiosis and various subcorneal pustules characterized by the presenceof intact neutrophils and degenerate and dermal edema hyalinizationmoderate collagen, likewise in TG staining, poor dermal collagen proliferationdisorganized with little presence of diffuse connective tissue wasobserved, while in the PR/P staining, areas of red birefringence was observed,indicating moderate presence of mature type I collagen (red brightpolarization). The diagnosis was based on clinical signs, histopathologicalfindings, differential diagnosis and response to medical treatment. In theliterature there are no reports of PF in the Department, so it is the firstreport of this disease in horses of Córdoba.Keywords: autoimmune, dermopathy, horses. prurit