Therapeutic management of feline hepatic lipidosis by Mycoplasma haemofelis
Abstract
Describe the therapeutic management of hepatic lipidosis in an infected feline Mycoplasma haemofelis and evaluation of therapeutic effectiveness in Colombia. A female cat, 1year old, breed Balinese, It has a fever, jaundice, lethargy, anorexia, lymphopenia and anemia hypochromic normocytic. Feline ultrasound showed hepatomegaly and liver changes echotexture, also values of liver enzymes. It was diagnosed with presence of Mycoplasma haemofelis, through direct smear. The cat was treated with doxycycline 10 mg/kg PO, every 24 hours, omeprazole 0.5 mg/kg for 30 days, dipyrone 28 mg/kg every 12 hours to control fever, metadoxine 10 mg/kg IV, every 12 hours for 30 days, oxipurina and orotic acid at doses of 4 mg/kg IM every 12 hours for 1 week and silymarin 50 mg/kg orally PO every 12 hours for 30 days. The patient after 20 days of treatment with doxycycline, metadoxine and silymarin, presented showedimprovement and recovered from hepatic lipidosis and was negative for the presence of Mycoplasma haemofelis, this case is described as being hepatic lipidosis other alterations to consider in mycoplasma infection in feline species and its therapeutic management.Downloads
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References
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Tasker S; Peters IR, Day MJ, Willi B, Hofmann R, et al. Distribution of Mycoplasma haemofelis in blood and tissues following experimental infection. Microb Pathog 2009; 47:334–340. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791849
Vásquez Frías R, Reyes García JG, Fernández Del Valle C, Anaya Reyes M, Rizzoli Córdoba A. Silimarina, ácido alfa-lipoico y Seleniometionina en el tratamiento de hígado graso: revisión sistemática de la literatura. Med Mex 2013; 58:37–46. http://www.medigraphic.com/pdfs/abc/bc-2013/bc131g.pdf
Veir JK, Lappin MR. Molecular diagnostic assays for infectious diseases in cats. Vet Clin Small Anim 2010; 40:1189–1200. http://www.ncbi.nlm.nih.gov/pubmed/20933144
Arias S, Suárez F, Álvarez I, Gutiérrez E, Castellanos I, Cardona L. Meningoencefalitis por histoplasmosis en un canino: reporte de caso. Rev Med Vet 2010; 20:39–47. http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0122-93542010000200004
Armstrong JP, Blanchard G. Hepatic lipidosis in cats. Vet Clin Small Anim 2009; 39:599–626. http://www.ncbi.nlm.nih.gov/pubmed/19524794
August J. Consultas en medicina interna felina. 5ª ed. Buenos Aires: Interamericana; 2008.
Botana LM, Landoni F, Jiménez TM. Farmacología y terapéutica veterinaria. 1ª ed. Madrid: McGraw-Hill Intermericana; 2002. http://docplayer.es/8399256-Farmacologia-y-terapeutica-veterinaria.html
Brunton L, Lazo J, Parjer KL. Goodman & Gilman The Pharmacological basis of therapeutics. 11a. ed. New York: McGraw Hill; 2007. https://www.amazon.com/Goodman-Gilmans-Pharmacological-Therapeutics-Twelfth/dp/0071624422
Caballería J, Parés A, Brú C, Mercader J, García-Plaza A. Metadoxine accelerates fatty liver recovery in alcoholic patients: results of a randomized double-blind, placebo-control trial. J Hepatol 1998; 28:54–60. http://www.ncbi.nlm.nih.gov/pubmed/9537864
Carvajal Parra DL. Frecuencia de infecciones rickettsiales y hemoparasitarias en gatos domésticos (Felis catus schereber 1775) de los Centros de Zoonosis, en las Ciudades de Bogotá y Cali. Tesis maestría. Universidad Nacional de Colombia, Bogotá, 2012. 125 p. http://www.bdigital.unal.edu.co/11123/
Center SA. Feline hepatic lipidosis. Vet Clin Small Anim 2005; 35:225–269. http://www.vetsmall.theclinics.com/
Dipiro JT, Talbert RL, Yee GC, Matzke GR, Well B, et al. Pharmacotherapy a pathophiologic approach. 9ª ed. Missouri: McGraw Hill; 2014. http://accesspharmacy.mhmedical.com/content.aspx?bookid=689§ionid=66575064
Ettinger S, Feldman E. Tratado de medicina interna veterinaria. 6ª ed. Madrid: Elsevier; 2007. Google books
Grant Maxie M. Jubb, Kennedy & Palmer’s Pathology of domestic animals. 5ª ed. Oxford: Saunders; 2007. https://www.amazon.com/Kennedy-Palmers-Pathology-Domestic-Animals/dp/0702028231
Guptill L. Feline Bartonellosis. Vet Clin Small Anim 2010; 40:1073–1090. http://www.ncbi.nlm.nih.gov/pubmed/20933137
Korman R, Cerón J, Barker E, Eckersall P, Tasker, S. Acute phase response to Mycoplasma haemofelis and “Candidatus Mycoplasma haemominutum” infection in FIV-infected and non-FIV-infected cats. Vet J 2012; 193:433–438. http://www.ncbi.nlm.nih.gov/pubmed/22763129
Nelson R, Couto G. Medicina interna de animales pequeños. 4ª ed. Buenos Aires: Interamericana; 2007.
Nyland T, Mattbon J. Diagnóstico ecográfico en pequeños animales. 2ª ed. Barcelona: Multimédica; 2002.
Ortiz Álvarez JF. Adenocarcinoma gástrico con metástasis a hígado y pulmón en un canino. J Agric Animal Sci 2013; 2:68–77. 2013. http://repository.lasallista.edu.co:8080/ojs/index.php/jals
Piccini A, Berardi S, Cammertoni N, Magi G, Mari S, Scarpona S, Ross G. Understanding the pathophysiology of feline hepatic lipidosis. J Comp Pathol 2015; 152:70. http://www.sciencedirect.com/science/journal/00219975
Plumb DC. Plumb´s Veterinary Drug Handbook. 7ª ed. Iowa: Wiley-blackwell; 2011. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500119/
Polyak SJ, Ferenci P, Pawlotsky JM. Hepatoprotective and antiviral functions of silymarin components in hepatitis C Virus infection. Hepatology 2013; 57:1262–1272. http://www.ncbi.nlm.nih.gov/pubmed/23213025
Senthil N, Nagarajan K, Padmanath K, Subapriya S, Vairamuthu S, et al. A rare case study on feline mycoplasmosis. IJVAST 2014; 3:106–108. Descarga
Sykes JE. Feline hemotropic mycoplasmas. Vet Clin Small Anim 2010; 40:1157–1170. http://www.ncbi.nlm.nih.gov/pubmed/20933142
Sykes JE. Feline hemotropic mycoplasmosis (feline hemobartonellosis). Vet Clin Small Anim 2003; 33:773–789. http://www.ncbi.nlm.nih.gov/pubmed/12910743
Tasker S; Peters IR, Day MJ, Willi B, Hofmann R, et al. Distribution of Mycoplasma haemofelis in blood and tissues following experimental infection. Microb Pathog 2009; 47:334–340. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791849
Vásquez Frías R, Reyes García JG, Fernández Del Valle C, Anaya Reyes M, Rizzoli Córdoba A. Silimarina, ácido alfa-lipoico y Seleniometionina en el tratamiento de hígado graso: revisión sistemática de la literatura. Med Mex 2013; 58:37–46. http://www.medigraphic.com/pdfs/abc/bc-2013/bc131g.pdf
Veir JK, Lappin MR. Molecular diagnostic assays for infectious diseases in cats. Vet Clin Small Anim 2010; 40:1189–1200. http://www.ncbi.nlm.nih.gov/pubmed/20933144
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Published
2016-09-10
How to Cite
Molina, V. M., & Pacheco, C. (2016). Therapeutic management of feline hepatic lipidosis by Mycoplasma haemofelis. CES Medicina Veterinaria Y Zootecnia, 11(2), 103–114. Retrieved from https://revistas.ces.edu.co/index.php/mvz/article/view/3965
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CASO CLÍNICO
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