Eficiência do exame ultrassonográfico transabdominal no auxílio ao diagnóstico precoce da colite dorsal direita induzida em equinos

Autores/as

  • Bruno Santos Cândido de Andrade Rua Bernardo Torres
  • Fabiane Cassou Curitiba
  • José Ramón Martinez Aranzales Universidad de Antioquia UdeA
  • Geraldo Eleno Silveira Alves Universidade Federal de Minas Gerais

Resumen

A Colite Dorsal Direita (CDD) é uma enteropatia caracterizada por inflamação, edema mural e ulcerações da mucosa do cólon dorsal direito de equinos. Sua ocorrência associa-se ao uso prolongado e/ou sobredoses de antiinflamatórios não esteroidais (AINEs), principalmente fenilbutazona (FBTZ). As alterações clínicas incluem anorexia, cólica, hipoproteinemia, neutropenia, endotoxemia, diarreia e perda de peso. O exame ultrassonográfico (EUS) é importante como auxílio no diagnóstico de anormalidades abdominais. Com o objetivo de avaliar a eficiência do EUS no diagnóstico precoce da CDD foram realizados EUS periódicos em cinco equinos (C1-C5) submetidos a protocolo experimental de colites. Cinco imagens ultrassonográficas por animal foram obtidas em dias alternados (D0-D14), entre o 11º e 15º espaços intercostais direitos e, em cada imagem, a espessura da parede do cólon dorsal direito foi mensurada em milímetros (mm) em quatro áreas diferentes. Não houve diferença entre D0 (3,4 ± 0,55 mm) e D3 (4,9 ± 1,79 mm), porém em D5 (7,17 ± 1,28 mm), D7 (7,00 ± 1,68 mm) e D9 (6,71 ± 2,27 mm), constatou-se aumento significativo da espessura da parede do cólon em relação a D0 e D3 (p≤0,05). Já que o início dos sinais clínicos importantes foi evidente nos animais somente em D9, concluiu-se que o EUS do cólon dorsal direito é sensível como método diagnóstico precoce da CDD.

 

Eficiencia del examen ecográfico transabdominal como ayuda en el diagnóstico precoz de la colitis dorsal derecha inducida en equinos

La Colitis Dorsal Derecha (CDD) es una enteropatía caracterizada por inflamación, edema de pared y ulceraciones de la mucosa del colon dorsal derecho de equinos. Su ocurrencia se asocia al uso prolongado o sobredosis de antinflamatorios no esteroides (Aines), principalmente la fenilbutazona (FBTZ). Las alteraciones clínicas incluyen anorexia, cólico, hipoproteinemia, neutropenia, endotoxemia, diarrea y pérdida de peso. El examen ecográfico (EET) es importante como auxilio diagnóstico de anormalidades abdominales. Con el objetivo de evaluar la eficiencia del EET en el diagnóstico precoz de CDD fueron realizados EET periódicos en cinco equinos (C1-C5) sometidos a un protocolo experimental de colitis. Cinco imágenes ecográficas por animal fueron obtenidas en días alternados (D0-D14); entre el 11º y 15º espacios intercostales derechos y en cada imagen, el espesor del colon dorsal derecho fue medido en milímetros (mm) en cuatro áreas diferentes. No hubo diferencia entre D0 (3,4 ± 0,55 mm) y D3 (4,9 ± 1,79 mm), sin embargo en D5 (7,17 ± 1,28 mm), D7 (7,00 ± 1,68 mm) y D9 (6,71 ± 2,27 mm), se estableció un aumento significativo del espesor de la pared del colon en relación a D0 y D3 (p≤0,05). Debido al inicio evidente de signos clínicos importantes solo a partir de D9, se concluye que el EET del colon dorsal derecho es sensible como método diagnóstico precoz de CDD.

Palabras clave: caballos, colitis dorsal derecha, ecografia, fenilbutazona.

 

Efficiency of transabdominal ultrasound examination in aid to early diagnosis of induced right dorsal colitis in horses┴

 

The Right Dorsal Colitis (CDD) is an enteropathy characterized by wall inflammation and edema and ulceration of the mucosa of the right dorsal colon in horses. Its occurrence is associated with prolonged use and/or overdoses of non-steroidal anti-inflammatory drugs (NSAIDs), especially phenylbutazone (FBTZ). Clinical abnormalities include anorexia, colic, hypoproteinemia, neutropenia, endotoxemia, diarrhea and weight loss. The ultrasound examination (EUS) is important in the diagnosis of abdominal abnormalities. Aiming to evaluate the efficiency of EUS in the early diagnosis of CDD, EUS were performed regularly in five horses (C1-C5) underwent protocol of induction experimental colitis. Five images per animal were taken on alternate days (D0-D14), between the 11th and 15th intercostal spaces in right side and, in each image, the wall thickness of the right dorsal colon was measured in millimeters (mm) at four different sites. There was no difference between D0 (3.4±0.55mm) and D3 (4.9 ± 1.79 mm), but in D5 (7.17 ± 1.28 mm), D7 (7.00 ± 1.68 mm) and D9 (6.71 ± 2.27 mm), there was significant increase in colon wall thickness in relation to D0 and D3 (p≤0.05). Since the onset of relevant clinical signs, such as diarrhea was evident in all animals only in D9, it was concluded that ultrasonography of the right dorsal colon is sensitive method as early diagnosis of CDD.

Keywords: horses, phenylbutazone, right dorsal colitis, ultrasound

 

DOI: http://dx.doi.org/10.21615/cesmvz.11.2.4

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Biografía del autor/a

Bruno Santos Cândido de Andrade, Rua Bernardo Torres

Faculdade de Vértice

Fabiane Cassou, Curitiba

Veterinaria autónoma

José Ramón Martinez Aranzales, Universidad de Antioquia UdeA

Grupo de InvestigaciónCENTAURO, Línea deInvestigación LIMCE, Escuelade Medicina Veterinaria,Facultad de Ciencias Agrarias.

Geraldo Eleno Silveira Alves, Universidade Federal de Minas Gerais

Departamento de Clínica eCirurgias Veterinárias, Escolade Veterinária,

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2016-09-09

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Cândido de Andrade, B. S., Cassou, F., Martinez Aranzales, J. R., & Silveira Alves, G. E. (2016). Eficiência do exame ultrassonográfico transabdominal no auxílio ao diagnóstico precoce da colite dorsal direita induzida em equinos. CES Medicina Veterinaria Y Zootecnia, 11(2), 51–60. Recuperado a partir de https://revistas.ces.edu.co/index.php/mvz/article/view/3961

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